Ian Lyall

Articles

CRISPR’s next act: Editors that rewrite single letters without cutting the DNA

Gene editing is moving beyond scissors. Base editing and prime editing can rewrite DNA with fewer cuts, sometimes changing a single letter. The appeal is precision, but delivery, off-target edits, mosaicism, and long-term monitoring will shape what “cure” can honestly mean.

Batteries, not brains: Bioelectricity and the new map of how bodies heal

At its simplest, bioelectricity is the difference in electrical charge across a cell’s membrane.

The immune system’s new teachers: Personalised cancer vaccines and the logistics of made-to-order medicine

Custom-built vaccines that train the immune system to recognise a patient’s own tumour mutations are moving from theory to clinic. Their promise is compelling; their delivery is anything but simple.

The end of antibiotics, again: phage therapy, bacteriocins, and precision antimicrobials

Antimicrobial resistance (AMR) is making routine infections harder to treat, but the “new antibiotics” story is no longer only about new pills. Phages, bacteriocins and other targeted antimicrobials could spare the microbiome. Their precision also complicates trials, manufacturing and payment.

Biology’s new supply chains: Why the future of biotech may be manufacturing, not discovery

Biotech likes to celebrate breakthroughs at the bench. Patients experience breakthroughs at the pharmacy, and that gap is mostly manufacturing. Scale-up, quality control, and fragile supply chains decide which therapies survive reality. Small process changes can quietly transform what is possible.

Apple explores AirTag-sized AI wearable as next frontier in personal computing

Analysts say the iPhone maker is developing a camera-equipped “AI pin” that could arrive later this decade, signalling a shift toward ambient, always-on computing and sharpening competition with OpenAI.

AI spending momentum at Davos points to 2026 inflexion year

The investment firm argues investor scepticism masks a surge in enterprise and government AI spending, with Big Tech capex and Nvidia-led demand signalling the next phase of the AI cycle.

Tesla drops standard Autopilot as Musk pushes drivers towards subscriptions

Meta switches off AI characters for teens amid mounting scrutiny

The Facebook owner has paused teen access to its AI characters worldwide, saying it wants to rebuild the feature with stronger parental controls as legal pressure over child safety intensifies.

Michael Burry and the meme stock. What the Big Short star thinks of GameStop

Time to buy? You decide

SpaceX aims for $1.5 trillion summer IPO

According to a report, Elon Musk expects to raise around $50 billion from the US listing

MoltBot Explained: The viral AI agent formerly ClawdBot

MoltBot is a local-first “personal AI agent” that lives in your messages and can touch your real accounts. It's powerful enough to feel like the future, sharp enough to cut you.

Apple’s rumoured January event: Refresh, or reset?

A widely shared leak video claims Apple is preparing a January 2026 event with up to nine products, including a cheaper MacBook and new M5 machines. If accurate, it would signal a shift in how Apple thinks about price, pace and platform reach.

Demis Hassabis: why AGI is closer than it looks, and further away than the hype suggests

A year ago, Silicon Valley was whispering about diminishing returns. Today, the chief executive of Google DeepMind says the question is no longer whether AI will work, but what kind of intelligence we are actually building

The new AI tech that aims to beat electricity grid constraints

Grid capacity is becoming the hard ceiling on AI scaling. Furiosa AI’s inference chip is designed to cut the watts per query by slashing memory traffic, keeping tensors on-chip, and trading GPU flexibility for purpose-built efficiency.

Anthropic’s CEO says AI is growing up fast. Society isn’t ready

Dario Amodei warns that artificial intelligence has entered a dangerous adolescence, with explosive capability gains racing far ahead of regulation, labour policy and democratic control.

OpenAI's $1trn IPO and what Amazon’s $50bn gambit reveals about the brutal race for AI supremacy

The reported investment discussions are less about loyalty and more about leverage, capacity and survival in an industry where no single partnership feels secure anymore.

Apple’s booming iPhone sales hide a harder truth about the AI hardware cycle

A strong Apple quarter and Nvidia’s continued dominance point to the same underlying constraint: access to scarce silicon, memory and substrates is now the real bottleneck in tech growth

Goodbye Moltbot: OpenClaw emerges as latest name for fast-growing personal AI assistant

The open source AI project formerly known as Clawdbot has adopted a new identity after a series of rapid rebrands and mounting community interest.

OnlyFans explores majority sale in $5.5 billion deal talks

The UK-based creator platform is in exclusive negotiations with a US investment firm, marking the latest attempt by its owner to partially exit the business.